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多病共存(简称共病)已成为全球范围内日益突出的公共卫生挑战,传统单一疾病诊疗模式难以应对其复杂性。中医凭借整体观念、辨证论治与治未病等思想,在共病防治中展现出独特优势。本文系统梳理了共病的概念演变、西医诊疗现状及其面临的机制不清、诊断困难、干预局限、多重用药与评估工具缺乏等问题,并提出中医应对共病的研究策略。重点围绕共病的核心病机与证候特征、证候诊断标准建立、个体化干预策略、疗效与预后评价工具研发等关键环节展开论述,强调“病证结合”与“以证统病”的研究思路,旨在为共病的中医临床研究提供理论依据与方法学支撑。
Abstract:Multimorbidity(referred to as comorbidity) has become an increasingly prominent global public health challenge,and the traditional single-disease diagnosis and treatment model struggles to address its complexity. Traditional Chinese Medicine(TCM),with its holistic concept,syndrome differentiation-based treatment,and preventive treatment theories,demonstrates unique advantages in the prevention and management of comorbidity. This article systematically reviews the evolution of the concept of comorbidity,the current status of western medical diagnosis and treatment,and the problems it faces,such as unclear mechanisms,diagnostic difficulties,limited interventions,polypharmacy,and a lack of assessment tools,and proposes research strategies for TCM in addressing comorbidity. The discussion focuses on key aspects including the core pathogenesis and syndrome characteristics of comorbidity,the establishment of syndrome diagnostic criteria,individualized intervention strategies,the development of tools for efficacy and prognosis evaluation,emphasizing the research ideas of "combining disease pattern and syndrome pattern" and "guiding disease treatment with syndromes". The aim is to provide theoretical foundations and methodological support for clinical research on comorbidity in TCM.
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基本信息:
DOI:10.16368/j.issn.1674-8999.2025.12.389
中图分类号:R24
引用信息:
[1]李建生,王佳佳.共病的中医临床研究策略[J].中医学报,2025,40(12):2487-2491.DOI:10.16368/j.issn.1674-8999.2025.12.389.
基金信息:
国家重点研发计划“中医药现代化”重点专项资助项目(2024YFC3505302); 河南省中医药科学研究专项资助项目(2023ZY2039); 河南省“双一流”创建学科中医学科学研究专项资助项目(HSRP-DFCTCM-2023-4-09)